American Scientists Awarded 2017 Nobel Prize for Medicine

American Scientists Awarded 2017 Nobel Prize for Medicine

American Scientists Awarded 2017 Nobel Prize for Medicine

The trio won the prize for 'their discoveries of molecular mechanisms controlling the circadian rhythm'. This is the internal cycle (circa is the Latin for "about" and dies the Latin for "day") that matches the body's physiology to the alternation of light and darkness caused by Earth's rotation.

The Nobel Prize in medicine for 2017 has been awarded for answering precisely these questions.

The existence of an inner clock has been known about since 1729 when French scientist Jean-Jaques d'Ortous de Mairan found that the daily movement of a plant's leaves to track the sun continued when it was kept in the dark.

One hour in each cell, like plants, animals, even mushrooms, human body is running a watch in nearly every cell.

In the mid of 1980, these three laureates tested the fruit flies for isolating gene, which can control the common biological rhythm and discovered the way of encoding a protein accumulated during the night in cell and degrades in a day. A decade later, Young discovered another "clock gene".

Most studies have also studied these clocks only in vertebrates and fruit flies, and there is growing interest - especially with the use of the latest gene-editing techniques - to explore how circadian rhythms work in invertebrates and plants.

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The clock also regulates sleep, which is critical for normal brain function.

Rosbach told the Associated Press "I'm still a little overwhelmed", adding "I stand on the shoulders of giants".

Young won the Nobel on Monday with fellow Americans Michael Rosbash and Jeffrey Hall for their discoveries about the body's biological clock. The degradation mediated by DOUBLETIME slows accumulation of the PER protein, helping to keep the 24-hour clock on time.

Hall was born in NY in 1945 and works at the University of Maine; Rosbash was born in Kansas in 1944 and works at Brandeis University in Waltham, Massachusetts, while Young, was born in Miami in 1949 and works at the Rockefeller University in NY.

Foster, who has long worked in the area of circadian rhythms, believes this research could provide the platform to help those with degenerative diseases as well as blindness and schizophrenia.

"I really had trouble even getting my shoes on this morning". "Since the seminal discoveries by the three laureates, circadian biology has developed into a vast and highly dynamic research field, with implications for our health and wellbeing", the Nobel citation said. Or more technically, it is the 24 hour internal clock running between your sleep and awake times. Our inner clock is able to adapt our physiology to different phases of the day and regulates functions such as behaviour, hormone levels, metabolism and sleep.

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