How High Doses of Ibuprofen May Impact Male Infertility

How High Doses of Ibuprofen May Impact Male Infertility

How High Doses of Ibuprofen May Impact Male Infertility

The scientist tested aspirin, Tylenol and ibuprofen.

A new joint Danish-French research project has discovered that taking the medicament for only 14 days can cause damage to men's testosterone production, reports DR Nyheder.

In addition to producing sperm, testicles secrete testosterone, the primary male hormone.

Those who took the ibuprofen were more likely to have indications of testicular problems - including a condition called compensated hypogonadism that affects reproductive health - meaning men are less likely to be able to father a child.

The condition is normally seen in older men and smokers, and is caused by the body having to boost testosterone levels because normal production in the testes is insufficient.

When the researchers measured the testosterone/luteinizing hormone (LH) ratio in the participants, they found that the ibuprofen group experienced an 18 percent ratio decrease after 14 days.

Next, the researchers tested the direct effect of ibuprofen on testicles, using samples that had been taken from organ donors.

Researchers found that young men who took ibuprofen in doses commonly used by athletes developed a hormonal condition linked to reduced fertility.

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The authors of the study point to the wide range of endocrine disorders that may result from fluctuations in or impairment of the pituitary-gonadal axis such as infertility, depression, heart disease, arthritis and diabetes.

'Several studies have shown mild analgesics exposure during foetal life is associated with anti-androgenic effects and congenital malformations.

As Forbes notes, this is the first study to provide evidence with regards to the negative impact of ibuprofen on testicular physiology.

Over that time, there were no significant changes in the testosterone levels found in the blood of the subjects.

However, because the study is small, more research is needed to confirm the results. So not only is the shrinking of your balls concerning on a personal level, it could also suggest you're going to die earlier.

Compensated hypogonadism can lead to fertility issues, muscle wastage, and erectile dysfunction.

If you are concerned about your levels of testosterone and your ibuprofen use, though, it's worth chatting to your GP so you can get checked out and find a way to deal with chronic aches and pains in a healthy way.

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